SciBase Holding AB (STO: SCIB), a company specializing in AI-driven devices for dermatology, announced that its Electrical Impedance Spectroscopy (EIS) technology will be the primary endpoint in a new study led by the National Institutes of Health (NIH) in collaboration with the Swiss Institute of Allergy and Asthma Research (SIAF). The study, named THREAT (Testing Harms Related to Exposure to Allergenic Toxins), aims to investigate the effects of environmental exposures on skin health.
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The research is detailed in an editorial in the peer-reviewed journal Allergy, titled "Exploring the Link Between Environmental Exposures and Disease via Direct Challenge." It involves healthy participants who will be exposed to various skin products containing sodium lauryl sulfate (SLS), and to bedding and clothing made from synthetic fibers. Some will also be exposed to products free of SLS and natural fiber textiles.
The study will evaluate how these exposures affect skin barrier function by measuring skin impedance with EIS technology. This method involves transmitting electrical signals at varying frequencies to gauge the skin's barrier status.
Key aspects of the study include the participation of 80 healthy volunteers and the assessment of everyday exposure to items such as detergents and personal care products. Alongside measuring skin impedance, the research will track molecular, microbiome, and inflammatory biomarkers over time.
Pia Renaudin, CEO of SciBase, expressed satisfaction that Nevisense technology is being utilized in this NIH-led initiative, noting that the importance of skin impedance as a primary endpoint underscores the relevance of EIS in evaluating skin barrier function. Renaudin stated that this initiative is a significant advancement for the company's role in dermatology and skin health research.